Welcome To Taj Active Pharmaceuticals Ingredients & Chemicals (api) Taj Pharmaceuticals Limited (Manufacturers) India
    About Worldwide  |     FAQs    |    Careers    |        Media Center  |    Taj Pharmaceuticals  World   |    TAJ Group
    Taj Active Pharmaceuticals Ingredients & Chemicals (api) Taj Pharmaceuticals Limited

chemicals suppliers

      India              Latin America/ Caribbean            Africa & Middle East              Asia              Russia              Europe  

Active Pharmaceutical Ingredients  TAJ PHARMACEUTICALS LIMITED  

Home    API   Pharmaceuticals API List    Chemicals    Manufacturing     Product Development    Product Search    Agro Chemicals
  Custom Pharma Services      Contact Us

BP - British Pharmacopoeia CP - Chinese Pharmacopoeia EP - European Pharmacopoeia JP - Japanese Pharmacopoeia USP - United States Pharmacopoeia
Product exploitation, including development, sales and offer for sale are performed where permissible by patent law. This presentation is not and should not constitute as an offer for sale in territories where it is not permitted by law.

Sodium Valproate manufacturers India exporter cas No. 1069-66-5 Sodium Valproate  suppliers from india companies Pharmaceuticals Drug from India Largest manufacturer Top Sodium Valproate import india Sodium Valproate export india Sodium Valproate buyer india Sodium Valproate seller India IP BP USP EP Sodium Valproate Raw material manufacturer india Sodium Valproate dealers india Sodium Valproate producer india Sodium Valproate API Active pharmaceuticals ingradients  Purchase Cheap Lowest Price COA MSDS certificate of Analysis wholesalers india Sodium Valproate suppliers india Sodium Valproate trader Drug india Sodium Valproate purchase india Sodium Valproate structure Sodium Valproate benefits Sodium Valproate pharmacy and drugs review api Sodium Valproate  active pharmaceutical ingredients suppliers pharmaceutical manufacturing pharmaceutical drugs pharmaceutical intermediates pharmaceutical chemicals pharmaceutical raw materials active pharmaceutical ingredients committee active pharmaceutical ingredients manufacturer construction chemicals manufacturers manufacturers of industrial chemicals chemicals suppliers chemicals Sodium Valproate  offers chemicals wholesalers exporters chemicals specialty chemicals chemicals Sodium Valproates indian chemical suppliers chemicals india company  Indian chemical manufacturers association chemical industries in India indian chemical company chemical factories india safety Sodium Valproates manufacturers India plastic Sodium Valproates manufacturers India definition of Sodium Valproate Sodium Valproate  synthesis Sodium Valproate  salt effects of Sodium Valproate clinical advantage of Sodium Valproate polymorphs of Sodium Valproate preparation of Sodium Valproate efficacy of Sodium Valproate beneficial effects of Sodium Valproate determination and validation of Sodium Valproate determination Sodium Valproate Sodium Valproate -Sodium Valproate side effect of Sodium Valproate polymorphs of Sodium Valproate level of Sodium Valproate Sodium Valproate process for preparing Sodium Valproate Sodium Valproate mg process for Sodium Valproate detailed info for Sodium Valproate catalog Sodium Valproate polymorphs of Sodium Valproate dosage of Sodium Valproate intermediate of Sodium Valproate Sodium Valproate powder supply Sodium Valproate Taj Pharmaceuticals Limited.


 Taj Active Pharmaceuticals Ingredients & Chemicals

   Bulk Drugs Pharmaceuticals
   Oseltamivir Phosphate
   Phenyl Propanolamine
   Morphine HCl
   Morphine sulphate
   Ephedrine (EPH)
   Pseudoephedrine hydrochloride
   Codeine base
   Codeine phosphate hemihydrate
   Zolpidem Tartrate
   Granisetron Hcl
   Ibandronate Sodium
   Imatinib Mesylate
   Irinotecan Hcl
   Lercanidipine Hcl
   Losartan Potassium
   Loteprednol Etabonate
   Magnesium Valproate
   Memantine Hcl
   Metamizol Magnesium
   Metformin Hcl
   Metoprolol Tartrate
   Mometasone Furoate
   Naltrexone Hcl
   Octreotide Acetate
   Ondansetron Base
   Ondansetron Hcl
   Pamidronate Disodium
   Raloxifene Hcl
   Rivastigmine Tartrate
   Sertraline Hcl
   Sodium Valproate
   Sildenafil Citrate
   Sumatriptan Succinate
   Tiagabine Hcl
   Tizanidine Hcl
   Tramadol Hcl
   Valproic Acid
   Venlafaxine Hcl
   Ziprasidone Hcl
   Zoledronic Acid
   Buprenorphine HCl
   Dihydrocodeine hydrogentartrate
   Ethylmorphine HCl
   Hydroxychloroquine sulphate
   Noscapine base
   Phenobarbital acid
   Phenobarbital sodium
   Pharmaceuticals API
   Amlodipine Besylate
   Atorvastatin Calcium
   Candesartan Cilaxetil
   Cetirizine Dihydrochloride
   Ciprofloxacin HCl
   Dextromethorphan Base
   Diltiazem HCl
   Domperidone Base
   Domperidone Maleate
   Doxazosin Mesylate
   Duloxetine HCl
   Enalapril Maleate
   Esomeprazole Magnesium
   Fexofenadine HCl
   Fluoxetine HCl
   Galantamine HBr
   Levo Cetirizine
   Losartan Potassium

delivering world-class generics


Sodium Valproate CAS number 1069-66-5

Sodium Valproate CAS number 1069-66-5

Molecular Structure

Sodium Valproate  Formula C8H15NaO2

Sodium Valproate

CAS number 1069-66-5

Formula C8H15NaO2
Molecular Weight 166.19
ATC code N03AG01
PubChem 14047
ChemSpider 13428
Chemical data

Mol. mass 166.20 g/mol
Pharmacokinetic data
Bioavailability ?
Protein binding 9095%
Metabolism 75% by CYP enzymes
Half life 918 hours
Excretion 20% excreted as glucuronide
  • CAS number 1069-66-5
  • Formula C8H15NaO2
  • Molecular Weight 166.19
  • ATC code N03AG01
  • Pub Chem 14047
  • Chem Spider 13428

Microbiological Test
Total plate count MAX 1000/g
Yeast&mold MAX 100/g
E.Coli Negative 

IUPAC Name: sodium 2-propylpentanoate | CAS Registry Number: 1069-66-5
Synonyms: Sodium valproate, Valproate sodium, Depakene, Epilim, Convulex, Eurekene, Labazene, Orfiril, Valerin, Natrium valproat, Selenica, Sodium 2-propylpentanoate, Valproic acid sodium salt, Dipropylacetate sodium, Sodium dipropylacetate, Depakene (TN), Selenica (TN), Sodium bispropylacetate, Valproic acid sodium, Valproinsaeure, natrium

Molecular Formula: C8H15NaO2 Molecular Weight: 166.193270 [g/mol]
H-Bond Donor: 0 H-Bond Acceptor: 2
Sodium valproate is indicated mainly for complex or pure absence seizure, it can also be kinds to treat myoclonia or assist to treat it. Which is white powder, slightly subastringent, soluble to water.

Sodium valproate (INN) or valproate sodium (USAN) is the sodium salt of Valproic acid and is an anticonvulsantanticonvulsant used in the treatment of epilepsy and bipolar disorder, as well as other psychiatric conditions requiring the administration of a mood stabilizer. The intravenous formulations are used when oral administration is not possible.

  • MF: C8H15NaO2
  • MW: 166.20 g/mol
  • Metabolism75% by CYP enzymes
  • Half life9-18 hours
  • Excretion: 20% excreted as glucuronide


  • Sodium valproate is the widely used an anti-epileptic drug in the pediatric population. Nausea, vomiting, anorexia, amenorrhoea, sedation, tremor, weight gain, alopecia, and hepato-toxicity are the most common side effects of this drug.The hepatotoxicity may manifest in several ways: transient elevation of transaminase values, reversible hyperammonemia with liver disease, or Reye syndrome - like syndrome, or progressive hepatitis.
  • Patients with epilepsy who are on sodium valproate have been reported to have low serum carnitine levels and this secondary carnitine deficiency has been reported in the literature. Prolonged treatment with sodium valproate more than other anticonvulsantsanticonvulsants, enhances renal losses of carnitine esters, lowers serum carnitine levels, and results in secondary carnitine deficiency.It also may cause a decrease in serum free carnitine levels by inhibition of plasmalemmal carnitine uptake.


This compound has been obtained by two different ways:

  • The reaction of dipropylcarbinoldipropylcarbinol with HBr gives 4-bromoheptane, which is treated with KCN to yield 2-propylpentanenitrilepropylpentanenitrile .Finally, this compound is hydrolyzed to the target compound with NaOH or with H2SO4.
  • The condensation of cyanacetic acid ethyl ester with propyl bromide by means of sodium propoxide in propanol gives crude dipropylcyanaaceticdipropylcyanaacetic acid ethyl ester, which, without isolation, is hydrolyzed with NaOH in hot water yielding dipropylcyanaceticdipropylcyanacetic acid .The decarboxylationdecarboxylation of dipropylcyanaceticdipropylcyanacetic acid at 140-

Safety Profile

All antiepilepic medications have been shown to be associated with higher risks of fetal abnormalities (mostly for spina bifida) since at least 1983 with the risks being related to the strength of medication used and use of more than one drug.Valproate has also been recognised as sometimes causing a specific facial changes ("facial phenotype") termed "fetal valproate syndrome".Sodium valproate has been associated with the rare condition paroxysmal tonic upgaze of childhood, also known as Ouvrier-Billson syndrome, from childhood or fetal exposure (this condition resolved after discontinuing valproate therapy)

Mechanism Of Toxic Effects

Valproate is a drug with anticonvulsant activity against a wide range of seizure types and appears to be well tolerated at therapeutic doses. In therapeutic use valproate's action may be related to altered turnover of GABA and actions on voltage sensitive sodium channels. The mechanisms involved in toxicity are unclear. It appears to have teratogenic effects in therapeutic doses.

Information Associated with Product:
Detail icon
Product Enquiry Product Quotation Sample Request Place Your Order  
Product Enquiry Product Quotation Sample Request Place Your Order  
   Phenyl acetic acid
   Propionic anhydride
   Para Methoxy Phenyl Acetone
   Para Methoxy Phenyl Acetic Acid
   Raspberry Ketone
   Benzyl Acetone
   Biphenyl (Phenyl benzene)
   Benzyl methyl ketone
   Bromo phenyl acetone (1-Bromo-1-phenyl-2-propanone)
   Denatonium Benzoate
   Anthranilic acid
   Gamma butyrolactone
   Acetic anhydride
   Diethyl ether
   Potassium permanganate
   Potassium permanganate
   Methyl isobutyl ketone
   Hydrochloric acid
   Para Anisyl Choride
   Para Anisic Acid
   Para Anisyl Bromide
   Para Anisoyl Acetone
   Methyl Tyramine
   Para Cresyl Acetate
   Para Cresyl Methyl Ether
   Anisyl Formate
   Ortho Anisic Aldehyde
   3-Aminopropyl Imidazole
   3-Benzyloxy Propionitrile
   1-Hydroxy Cyclohexyl-4-Methoxyphenylacetonitrile
   Manganese Sulphate Monohydrate
   Pharmaceuticals API
   Rabeprazole Sodium
   Ranitidine Hydrochloride
   Rivastigmine Tartrate
   Rosiglitazone Maleate
   Sevelamer hydrochloride
   Tamsulosin HCl
   Tegaserod Maleate
   Terbinafine HCl
   Tolterodine Tartrate
   Montelukast Sodium
   Moxifloxacin HCl
   Nandrolone Decanoate
   Omeprazole Sodium
   Pantoprazole Sodium
   Quetiapine Fumarate
   Quinine Sulfate
   Metoprolol Succinate
   Betalactams Piperacillin
   Cefditoren Pivoxil
   Cefazolin Sodium
   Cefuroxime Sodium
   Cefoxitin Sodium
   Cefotetan Sodium
   Cefotaxime Sodium
   Cefoperazone Sodium
   Ceftizoxime Sodium



Home Page Company Profile Our Products     Amlodpine Besylates     Atorvastatin Calcium     Caffeine     Clopidogrel Bisulfate     Clomipramine HCL     Losartan Potassium     Metformin Hcl     Nandrolone Decanoate     Pantoprazole Sodium     Pseudoephedrine Hydrochloride     Quinine Sulfate     Ramipril     Ranitidine Hydrochloride     Sertraline Hcl     Sevelamer Hydrochloride     Sodium Valproate     Testosterone     Theophyline     Valsartan     Toluene     Benzyl Chloride     Ethanol     Modafinil     Para Methoxy Phenyl Acetone     Anthranilic Acid

Copyright Taj Pharmaceuticals Ltd. | Privacy Policy | Terms & Conditions |


2004 - 2009 Taj Pharmaceuticals Limited . All rights reserved
Active Pharmaceutical Ingredients manufacturer, exporter, drug ingredients, pharmaceuticals, India
Note:-We are committed to helping you find the right answers to your questions and concerns. However, this web site is not intended to give investment advice, promote the use of Taj Pharmaceuticals  Ltd products or provide information on which to base medical treatment. If you have questions regarding any Taj Pharmaceuticals  Ltd product or are experiencing a medical emergency, please consult your health care provider.
Additionally, contact information on this web site cannot be used to report adverse drug events. If you are a physician, please follow the procedures required by your country's regulations. Please choose one of the given options to contact us and we will respond to your inquiry as quickly as possible.