Welcome To Taj Active Pharmaceuticals Ingredients & Chemicals (api) Taj Pharmaceuticals Limited (Manufacturers) India
    About Worldwide  |     FAQs    |    Careers    |        Media Center  |    Taj Pharmaceuticals  World   |    TAJ Group
    Taj Active Pharmaceuticals Ingredients & Chemicals (api) Taj Pharmaceuticals Limited

chemicals suppliers

      India              Latin America/ Caribbean            Africa & Middle East              Asia              Russia              Europe  

Active Pharmaceutical Ingredients  TAJ PHARMACEUTICALS LIMITED  

Home    API   Pharmaceuticals API List    Chemicals    Manufacturing     Product Development    Product Search    Agro Chemicals
  Custom Pharma Services      Contact Us

BP - British Pharmacopoeia CP - Chinese Pharmacopoeia EP - European Pharmacopoeia JP - Japanese Pharmacopoeia USP - United States Pharmacopoeia
***
Product exploitation, including development, sales and offer for sale are performed where permissible by patent law. This presentation is not and should not constitute as an offer for sale in territories where it is not permitted by law.

Tramadol manufacturers India exporter cas No. 27203-92-5 Tramadol  suppliers from india companies Pharmaceuticals Drug from India Largest manufacturer Top Tramadol import india Tramadol export india Tramadol buyer india Tramadol seller India IP BP USP EP Tramadol Raw material manufacturer india Tramadol dealers india Tramadol producer india Tramadol API Active pharmaceuticals ingradients  Purchase Cheap Lowest Price COA MSDS certificate of Analysis wholesalers india Tramadol suppliers india Tramadol trader Drug india Tramadol purchase india Tramadol structure Tramadol benefits Tramadol pharmacy and drugs review api Tramadol  active pharmaceutical ingredients suppliers pharmaceutical manufacturing pharmaceutical drugs pharmaceutical intermediates pharmaceutical chemicals pharmaceutical raw materials active pharmaceutical ingredients committee active pharmaceutical ingredients manufacturer construction chemicals manufacturers manufacturers of industrial chemicals chemicals suppliers chemicals Tramadol  offers chemicals wholesalers exporters chemicals specialty chemicals chemicals Tramadols indian chemical suppliers chemicals india company  Indian chemical manufacturers association chemical industries in India indian chemical company chemical factories india safety Tramadols manufacturers India plastic Tramadols manufacturers India definition of Tramadol Tramadol  synthesis Tramadol  salt effects of Tramadol clinical advantage of Tramadol polymorphs of Tramadol preparation of Tramadol efficacy of Tramadol beneficial effects of Tramadol determination and validation of Tramadol determination Tramadol Tramadol -Tramadol side effect of Tramadol polymorphs of Tramadol level of Tramadol Tramadol process for preparing Tramadol Tramadol mg process for Tramadol detailed info for Tramadol catalog Tramadol polymorphs of Tramadol dosage of Tramadol intermediate of Tramadol Tramadol powder supply Tramadol Taj Pharmaceuticals Limited.

 

 Taj Active Pharmaceuticals Ingredients & Chemicals

   Bulk Drugs Pharmaceuticals
   Chemicals
   Oseltamivir Phosphate
   Phenyl Propanolamine
   Phenylephrine
   Etafedrine
   Theophylline
   Tramadol
   Methylphenidate
   Morphine HCl
   Morphine sulphate
   Ephedrine (EPH)
   Pseudoephedrine hydrochloride
   Codeine base
   Codeine phosphate hemihydrate
   Zolpidem Tartrate
   Caffeine
   Gabapentin
   Gemcitabine
   Glimepiride
   Granisetron Hcl
   Ibandronate Sodium
   Imatinib Mesylate
   Irbesartan
   Irinotecan Hcl
   Isradipine
   Lamotrigine
   Lercanidipine Hcl
   Letrozole
   Losartan Potassium
   Loteprednol Etabonate
   Magnesium Valproate
   Meloxicam
   Memantine Hcl
   Mesalazine
   Metamizol Magnesium
   Metaxalone
   Metformin Hcl
   Metoprolol Tartrate
   Mifepristone
   Mirtazapine
   Modafinil
   Mometasone Furoate
   Naltrexone Hcl
   Netaglinide
   Octreotide Acetate
   Olanzapine
   Ondansetron Base
   Ondansetron Hcl
   Oxaliplatin
   Oxcarbazepine
   Oxethazaine
   Pamidronate Disodium
   Pentoxifylline
   Perindopril
   Pioglitazone
   PiroxicamBetacyclodextrine
   Raloxifene Hcl
   Repaglinide
   Rivastigmine Tartrate
   Ropinirole
   Sertraline Hcl
   Sodium Valproate
   Sildenafil Citrate
   Sumatriptan Succinate
   Temozolomide
   Terlipressin
   Testosterone
   Tiagabine Hcl
   Tizanidine Hcl
   Topiramate
   Tramadol Hcl
   Valproic Acid
   Venlafaxine Hcl
   Ziprasidone Hcl
   Zoledronic Acid
   Acenocoumarol
   Aluminium-magnesium-hydroxy-carbonate-hexahydrate
   Buprenorphine HCl
   Dihydrocodeine hydrogentartrate
   Ethylmorphine HCl
   Glibornuride
   Hydroxychloroquine sulphate
   Noroxymorphone
   Noscapine base
   Oxycodone
   Oxymorphone
   Phenobarbital acid
   Phenobarbital sodium
   Thebaine
   Pharmaceuticals API
   Alfuzosin
   Amlodipine Besylate
    Aripiprazole
   Atorvastatin Calcium
   Caffeine
   Candesartan Cilaxetil
   Cefdinir
   Cetirizine Dihydrochloride
   Ciprofloxacin HCl
   Dextromethorphan Base
   Diltiazem HCl
   Domperidone Base
   Domperidone Maleate
   Doxazosin Mesylate
   Duloxetine HCl
   Dutasteride
   Enalapril Maleate
   Esomeprazole Magnesium
   Famotidine
   Fexofenadine HCl
   Fluconazole
   Fluoxetine HCl
   Galantamine HBr
   Ibuprofen
   Lacidipine
   Lamotrigine
   Lansoprazole
   Levetiracetam
   Levo Cetirizine
   Levofloxacin
   Loratadine
   Losartan Potassium
 
   

delivering world-class generics

 

Tramadol Logo

Tramadol cas No. 27203-92-5

Tramadol Formula : C16H25NO2 Systematic (IUPAC) name
(1R,2R)-rel-2-[(dimethylamino)methyl]- 1-(3-methoxyphenyl)cyclohexanol
Identifiers

CAS number : 27203-92-5
ATC code : N02AX02
PubChem : 33741
DrugBank : APRD00028
ChemSpider : 31105

Chemical data
Formula : C16H25NO2
Mol. mass : 263.4 g/mol
SMILES : eMolecules & PubChem
Pharmacokinetic data
Bioavailability 68–72% Increases with repeated dosing.
Protein binding 20%
Metabolism Hepatic demethylation and glucuronidation
Half life 5–7 hours
Excretion Renal

Tramadol is a centrally acting analgesic, used for treating moderate to severe pain. It is often categorized as an opioid, although it is chemically not related to the opioid class of drugs. It does, however, appear to have agonist actions at the μ-opioid receptor as well as the noradrenergic and serotonergic systems.

Tramadol is used to treat moderate to moderately severe pain and most types of neuralgia, including trigeminal neuralgiaIt has been suggested that tramadol could be effective for alleviating symptoms of depression, anxiety, and phobias because of its action on the noradrenergic and serotonergic systems.However, health professionals have not yet fully endorsed of its use on a large scale for these disorders, although it may be used when other treatments have failed.


tramadol hydrochlorideTramadol is a centrally acting analgesic. The chemical name for tramadol hydrochloride is (±)cis-2-[(dimethylamino)methyl]-1-(3-methoxyphenyr) cyclohexanol hydrochloride.Tramadol hydrochloride is a white, bitter, crystalline and odorless powder. It is readily soluble in water and ethanol and has a pKa of 9.41. The n-octanol/water log partition coefficient (logP) is 1.35 at pH 7.

How should this medicine be used?

Tramadol comes as a tablet and an extended-release (long-acting) tablet to take by mouth. The regular tablet is usually taken with or without food every 4-6 hours as needed. The extended-release tablet should be taken once a day. Take the extended-release tablet at about the same time of day every day, and either always take it with food or always take it without food. Take tramadol exactly as directed. Do not take more medication as a single dose or take more doses per day than prescribed by your doctor. Taking more tramadol than prescribed by your doctor may cause serious side effects or death.

Your doctor may start you on a low dose of tramadol and gradually increase the amount of medication you take, not more often than every 3 days if you are taking the regular tablets or every 5 days if you are taking the extended-release tablets.

Swallow the extended-release tablets whole; do not split, chew, or crush them. Do not snort (inhale powder from crushed tablet) or inject the dissolved extended-release tablets. Taking this medication in a way that is not recommended may cause serious side effects or death.

Tramadol can be habit-forming. Do not take a larger dose, take it more often, or take it for a longer period of time than prescribed by your doctor. Call your doctor if you find that you want to take extra medication or if you notice any other unusual changes in your behavior or mood.

Tramadol side effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using tramadol and call your doctor at once if you have any of these serious side effects:

* seizure (convulsions);
* a red, blistering, peeling skin rash; or
* shallow breathing, weak pulse.

Less serious side effects may include:

* dizziness, drowsiness, weakness;
* nausea, vomiting, constipation, loss of appetite;
* blurred vision;
* flushing (redness, warmth, or tingly feeling); or
* sleep problems (insomnia).

Availability

Tramadol is usually marketed as the hydrochloride salt (tramadol hydrochloride); the tartrate is seen on rare occasions, and tramadol is available in both injectable (intravenous and/or intramuscular) and oral preparations. It is also available in conjunction with acetaminophen. The solutions suitable for injection are used in Patient-Controlled Analgesia pumps under some circumstances, either as the sole agent or along with another agent such as morphine.

Tramadol comes in many forms, including:

* capsules
* tablets
* extended-release tablets
* extended-release capsules
* chewable tablets
* low-residue and/or uncoated tablets that can be taken by the sublingual and buccal routes
* suppositories
* effervescent tablets and powders
* ampoules of sterile solution for SC, IM, and IV injection
* preservative-free solutions for injection by the various spinal routes (epidural, intrathecal, caudal, and others)
* powders for compounding
* liquids both with and without alcohol for oral and sublingual administration, available in regular phials and bottles, dropper bottles, bottles with a pump similar to those used with liquid soap and phials with droppers built into the cap
* tablets and capsules containing paracetamol (acetaminophen) and aspirin and other agents

Tramadol has been experimentally used in the form of an ingredient in multi-agent topical gels, creams, and solutions for nerve pain, rectal foam, concentrated retention enaema, and a skin plaster (transdermal patch) quite similar to those used with lidocaine.

Veterinary Use

Tramadol is used to treat post-operative, injury-related, and chronic (e.g., cancer-related) pain in dogs and cats [8] as well as rabbits, coatis, many small mammals including rats and flying squirrels, guinea pigs, ferrets, and raccoons. Tramadol comes in ampoules in addition to the tablets, capsules, powder for reconstitution, and oral syrups and liquids; the fact that its characteristic taste is not very bitter and can be masked in food and diluted in water makes for a number of means of administration. No data that would lead to a definitive determination of the efficacy and safety of tramadol in reptiles or amphibians is available at this time, and, following the pattern of all other drugs, it appears that tramadol can be used to relieve pain in marsupials such as North American opossums, Short-Tailed Opossums, sugar gliders, wallabies, and kangaroos among others.

Metabolism

Tramadol undergoes hepatic metabolism via the cytochrome P450 isozyme CYP2D6, being O- and N-demethylated to five different metabolites. Of these, M1 (O-Desmethyltramadol) is the most significant since it has 200 times the μ-affinity of (+)-tramadol, and furthermore has an elimination half-life of nine hours, compared with six hours for tramadol itself. In the 6% of the population that have slow CYP2D6 activity, there is therefore a slightly reduced analgesic effect. Phase II hepatic metabolism renders the metabolites water-soluble, which are excreted by the kidneys. Thus, reduced doses may be used in renal and hepatic impairment.

Tramadol is used to treat post-operative, injury-related, and chronic pain
Note: These API/ chemicals are designated as those that are used in the manufacture of the controlled substances and are important to the manufacture of the substances. For any (Control Substance) products Import and Export *** subjected to your country government laws /control substance ACT.
Note /Government Notification: These chemicals are designated as those that are used in the manufacture of the controlled substances and are important to the manufacture of the substances. For any (Control Substance) products Import and Export *** subjected to your country government laws /control substance ACT.
Information:  The information on this web page is provided to help you to work safely, but it is intended to be an overview of hazards, not a replacement for a full Material Safety Data Sheet (MSDS). MSDS forms can be downloaded from the web sites of many chemical suppliers. ,also that the information on the PTCL Safety web site, where this page was hosted, has been copied onto many other sites, often without permission. If you have any doubts about the veracity of the information that you are viewing, or have any queries, please check the URL that your web browser displays for this page. If the URL begins "www.tajapi.com/www/Denatonium Benzoate.htm/" the page is maintained by the Safety Officer in Physical Chemistry at Oxford University. If not, this page is a copy made by some other person and we have no responsibility for it.
The Controlled Substances Act (CSA) was enacted into law by the Congress of the United States as Title II of the Comprehensive Drug Abuse Prevention and Control Act of 1970.[1] The CSA is the federal U.S. drug policy under which the manufacture, importation, possession, use and distribution of certain substances is regulated. The Act also served as the national implementing legislation for the Single Convention on Narcotic Drugs.

 

 
             

   
  PDF DOWNLOAD                WORD DOCUMENT                 TEXT FILE

 
Product Enquiry Product Quotation Sample Request Place Your Order    
Product Enquiry Product Quotation Sample Request Place Your Order
 
   Chemicals
   Ethanol
   Phenyl acetic acid
   3,4-methylenedioxyphenyl-2-propanone
   Pseudoephedrine
   Piperidine
   Methylamine
   Propionic anhydride
   Para Methoxy Phenyl Acetone
   Para Methoxy Phenyl Acetic Acid
   Raspberry Ketone
   Benzyl Acetone
   Tyramine
   Biphenyl (Phenyl benzene)
   1-phenyl-1-hexanone
   Benzene
   Benzyl methyl ketone
   Bromo phenyl acetone (1-Bromo-1-phenyl-2-propanone)
   3'-Aminoacetophenone
   3'-Chloroacetophenone
   Toluene
   Denatonium Benzoate
   Anthranilic acid
   Ephedrine
   Ergonovine
   Ergotamine
   Hydroiodic
   Norpseudoephedrine
   Phenylpropanolamine
   Phosphorus
   Benzaldehyde
   Nitroethane
   Gamma butyrolactone
   N-Phenethyl-4-piperidinone
   Methylamine
   Ethylamine
   Isosafrole
   Safrole
   Piperonal
   N-methylephedrine
   N-methylpseudoephedrine
   Acetic anhydride
   Diethyl ether
   Potassium permanganate
   2-butanone
   Toluene
   Potassium permanganate
   2-butanone
   Methyl isobutyl ketone
   Hydrochloric acid
   Para Anisyl Choride
   Para Anisic Acid
   Para Anisyl Bromide
   Para Anisoyl Acetone
   Methyl Tyramine
   Tyramine
   Para Cresyl Acetate
   Para Cresyl Methyl Ether
   Anisyl Formate
   Ortho Anisic Aldehyde
   3-Aminopropyl Imidazole
   3-Benzyloxy Propionitrile
   1-Hydroxy Cyclohexyl-4-Methoxyphenylacetonitrile
   Veratrol
   Manganese Sulphate Monohydrate
   Pharmaceuticals API
   Rabeprazole Sodium
   Ramipril
   Ranitidine Hydrochloride
   Risperidone
   Rivastigmine Tartrate
   Rizatriptan 
   Rosiglitazone Maleate
   Sevelamer hydrochloride
   Telmisartan
   Tamsulosin HCl
   Tegaserod Maleate
   Terbinafine HCl
   Testosterone
   Tolterodine Tartrate
   Trandolapril 
   Montelukast Sodium
   Moxifloxacin HCl
   Naproxen
   Naratriptan
   Norfloxacin
   Nizatidine
   Nandrolone Decanoate
   Olmesartan
    Omeprazole
   Omeprazole Sodium
   Oxaprozin
   Paroxetine
   Pantoprazole Sodium
   Primidone
   Quetiapine Fumarate
   Quinine Sulfate
   Metoprolol Succinate
   Valdecoxib
   Valsartan
   Venlafaxine
   Voriconazole
   Zolmitriptan 
   Zonisamide
   Betalactams Piperacillin
   Tazobactam
   Meropenem
   Cefalexin
   Cefradine
   Cefadroxil
   Cefprozil
   Cefixime
   Ceftibuten
   Cefditoren Pivoxil
   Cefazolin Sodium
   Cefuroxime Sodium
   Cefoxitin Sodium
   Cefotetan Sodium
   Cefotaxime Sodium
   Cefoperazone Sodium
   Ceftizoxime Sodium

 

 

Home Page Company Profile Our Products     Amlodpine Besylates     Atorvastatin Calcium     Caffeine     Clopidogrel Bisulfate     Clomipramine HCL     Losartan Potassium     Metformin Hcl     Nandrolone Decanoate     Pantoprazole Sodium     Pseudoephedrine Hydrochloride     Quinine Sulfate     Ramipril     Ranitidine Hydrochloride     Sertraline Hcl     Sevelamer Hydrochloride     Sodium Valproate     Testosterone     Theophyline     Valsartan     Toluene     Benzyl Chloride     Ethanol     Modafinil     Para Methoxy Phenyl Acetone     Anthranilic Acid

Copyright © Taj Pharmaceuticals Ltd. | Privacy Policy | Terms & Conditions |
Sitemap

   
 

© 2004 - 2019 Taj Pharmaceuticals Limited . All rights reserved
Active Pharmaceutical Ingredients manufacturer, exporter, drug ingredients, pharmaceuticals, India
Note:-We are committed to helping you find the right answers to your questions and concerns. However, this web site is not intended to give investment advice, promote the use of Taj Pharmaceuticals  Ltd products or provide information on which to base medical treatment. If you have questions regarding any Taj Pharmaceuticals  Ltd product or are experiencing a medical emergency, please consult your health care provider.
Additionally, contact information on this web site cannot be used to report adverse drug events. If you are a physician, please follow the procedures required by your country's regulations. Please choose one of the given options to contact us and we will respond to your inquiry as quickly as possible.